| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIY15580.1 | AIY17454.2 | KR76_00075 | KR76_13050 | DNA-cytosine methyltransferase. | 5'-methylthioadenosine nucleosidase. | 0.903 |
| AIY15580.1 | AIY18433.2 | KR76_00075 | KR76_19725 | DNA-cytosine methyltransferase. | Signal peptidase I. | 0.900 |
| AIY15580.1 | dcm | KR76_00075 | KR76_01815 | DNA-cytosine methyltransferase. | Modification methylase ScrFIA; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.900 |
| AIY16864.2 | AIY17057.2 | KR76_08975 | KR76_10405 | Cystathionine beta-synthase. | Homoserine dehydrogenase. | 0.881 |
| AIY16864.2 | AIY18433.2 | KR76_08975 | KR76_19725 | Cystathionine beta-synthase. | Signal peptidase I. | 0.900 |
| AIY16864.2 | AIY18566.2 | KR76_08975 | KR76_20640 | Cystathionine beta-synthase. | Cystathionine gamma-lyase. | 0.996 |
| AIY16864.2 | ilvA | KR76_08975 | KR76_23620 | Cystathionine beta-synthase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.922 |
| AIY16864.2 | metH | KR76_08975 | KR76_13275 | Cystathionine beta-synthase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.960 |
| AIY16864.2 | metY | KR76_08975 | KR76_18085 | Cystathionine beta-synthase. | O-acetylhomoserine aminocarboxypropyltransferase. | 0.967 |
| AIY16864.2 | thrB | KR76_08975 | KR76_10415 | Cystathionine beta-synthase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.822 |
| AIY17057.2 | AIY16864.2 | KR76_10405 | KR76_08975 | Homoserine dehydrogenase. | Cystathionine beta-synthase. | 0.881 |
| AIY17057.2 | AIY18433.2 | KR76_10405 | KR76_19725 | Homoserine dehydrogenase. | Signal peptidase I. | 0.800 |
| AIY17057.2 | AIY18566.2 | KR76_10405 | KR76_20640 | Homoserine dehydrogenase. | Cystathionine gamma-lyase. | 0.900 |
| AIY17057.2 | ilvA | KR76_10405 | KR76_23620 | Homoserine dehydrogenase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.508 |
| AIY17057.2 | metH | KR76_10405 | KR76_13275 | Homoserine dehydrogenase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.965 |
| AIY17057.2 | metY | KR76_10405 | KR76_18085 | Homoserine dehydrogenase. | O-acetylhomoserine aminocarboxypropyltransferase. | 0.892 |
| AIY17057.2 | thrB | KR76_10405 | KR76_10415 | Homoserine dehydrogenase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
| AIY17454.2 | AIY15580.1 | KR76_13050 | KR76_00075 | 5'-methylthioadenosine nucleosidase. | DNA-cytosine methyltransferase. | 0.903 |
| AIY17454.2 | AIY18433.2 | KR76_13050 | KR76_19725 | 5'-methylthioadenosine nucleosidase. | Signal peptidase I. | 0.900 |
| AIY17454.2 | dcm | KR76_13050 | KR76_01815 | 5'-methylthioadenosine nucleosidase. | Modification methylase ScrFIA; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.914 |
