STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIY19335.1Biotin carboxyl carrier protein. (77 aa)    
Predicted Functional Partners:
AIY18301.2
Propionyl-CoA carboxylase beta chain.
 
 0.979
accD_1
Acetyl-coenzyme A carboxyl transferase alpha chain.
  
 
 0.939
leuA_2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.939
cimA
(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.939
accD_2
Acetyl-coenzyme A carboxyl transferase alpha chain.
  
 
 0.939
fabH
3-oxoacyl-(acyl carrier protein) synthase.
  
 
 0.932
AIY15958.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.922
AIY19115.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.922
AIY19281.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.922
acs_2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.918
Your Current Organism:
Pimelobacter simplex
NCBI taxonomy Id: 2045
Other names: ATCC 6946, Arthrobacter simplex, CCUG 23611, CIP 82.106, Corynebacterium simplex, DSM 20130, HAMBI 90, IFO 12069, KCTC 9106, LMG 16261, LMG:16261, NBRC 12069, NCIB 8929, NCIB:8929, Nocardioides simplex, P. simplex
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