STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cshCrispr-associated protein, Csh2 family; Identified by match to protein family HMM PF05107; match to protein family HMM TIGR01595; match to protein family HMM TIGR02590. (315 aa)    
Predicted Functional Partners:
cas5h
Crispr-associated protein Cas5, hmari subtype; Identified by match to protein family HMM TIGR02592; match to protein family HMM TIGR02593.
 
  
 0.956
ACN98263.1
Crispr-associated helicase Cas3; Identified by match to protein family HMM PF00271; match to protein family HMM TIGR01587.
 
  
 0.955
ACN98938.1
Crispr-associated protein, family; Identified by match to protein family HMM PF09484; match to protein family HMM TIGR02556; match to protein family HMM TIGR02591.
 
    0.954
cas_3
Crispr-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
 
   
 0.630
ACN99643.1
Crispr-associated protein Cas1; Identified by match to protein family HMM PF01867.
 
     0.617
cas2-2
Crispr-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.598
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.526
birA
biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.526
ACN98974.1
Hypothetical protein; Identified by Glimmer3; putative.
     
 0.459
ACN98661.1
Crispr-associated protein Cas1.
 
     0.431
Your Current Organism:
Sulfurihydrogenibium azorense
NCBI taxonomy Id: 204536
Other names: Aquificaceae bacterium Az-Fu1, S. azorense Az-Fu1, Sulfurihydrogenibium azorense Az-Fu1, Sulfurihydrogenibium azorense str. Az-Fu1, Sulfurihydrogenibium azorense strain Az-Fu1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.