node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HEAR0109 | HEAR0110 | HEAR0109 | HEAR0110 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA-3-methyladenine glycosylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.519 |
HEAR0109 | ogt | HEAR0109 | HEAR0111 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.452 |
HEAR0110 | HEAR0109 | HEAR0110 | HEAR0109 | DNA-3-methyladenine glycosylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.519 |
HEAR0110 | HEAR1287 | HEAR0110 | HEAR1287 | DNA-3-methyladenine glycosylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative DNA-3-methyladenine glycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.926 |
HEAR0110 | ogt | HEAR0110 | HEAR0111 | DNA-3-methyladenine glycosylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.971 |
HEAR0110 | tag | HEAR0110 | HEAR0071 | DNA-3-methyladenine glycosylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA-3-methyladenine glycosylase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.509 |
HEAR1287 | HEAR0110 | HEAR1287 | HEAR0110 | Putative DNA-3-methyladenine glycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA-3-methyladenine glycosylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.926 |
HEAR1287 | ogt | HEAR1287 | HEAR0111 | Putative DNA-3-methyladenine glycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.915 |
lpxB | ogt | HEAR1348 | HEAR0111 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.544 |
ogt | HEAR0109 | HEAR0111 | HEAR0109 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.452 |
ogt | HEAR0110 | HEAR0111 | HEAR0110 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DNA-3-methyladenine glycosylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.971 |
ogt | HEAR1287 | HEAR0111 | HEAR1287 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Putative DNA-3-methyladenine glycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.915 |
ogt | lpxB | HEAR0111 | HEAR1348 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.544 |
ogt | tag | HEAR0111 | HEAR0071 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DNA-3-methyladenine glycosylase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.757 |
tag | HEAR0110 | HEAR0071 | HEAR0110 | DNA-3-methyladenine glycosylase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | DNA-3-methyladenine glycosylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.509 |
tag | ogt | HEAR0071 | HEAR0111 | DNA-3-methyladenine glycosylase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.757 |