STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erpAIron-binding protein ErpA (Iron-sulfur cluster insertion protein); Required for insertion of 4Fe-4S clusters. (116 aa)    
Predicted Functional Partners:
iscU
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.867
hscB
Co-chaperone protein HscB (Hsc20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.799
iscR
Iron-sulfur cluster assembly transcription factor IscR; Function of strongly homologous gene; regulator.
  
  
 0.791
HEAR3019
Putative glutaredoxin-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.782
nsrR
HTH-type transcriptional regulator nsrR; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
  
 0.766
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 0.714
narH
Nitrate reductase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.711
narG
Nitrate reductase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
      
 0.679
bfr
Bacterioferritin (BFR) (Cytochrome b-557.5); Iron-storage protein.
     
 0.678
HEAR0244
Conserved hypothetical protein, putative protein CcmA; Homologs of previously reported genes of unknown function.
       0.665
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
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