node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HEAR0274 | HEAR0276 | HEAR0274 | HEAR0276 | Putative permease of the drug/metabolite transporter (DMT) superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Hypothetical protein; No homology to any previously reported sequences. | 0.420 |
HEAR0274 | folE2 | HEAR0274 | HEAR0280 | Putative permease of the drug/metabolite transporter (DMT) superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.559 |
HEAR0274 | ispA | HEAR0274 | HEAR0278 | Putative permease of the drug/metabolite transporter (DMT) superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Geranyltranstransferase (Farnesyl-diphosphate synthase) (FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.408 |
HEAR0274 | xseB | HEAR0274 | HEAR0277 | Putative permease of the drug/metabolite transporter (DMT) superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Exodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) (XseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.511 |
HEAR0276 | HEAR0274 | HEAR0276 | HEAR0274 | Hypothetical protein; No homology to any previously reported sequences. | Putative permease of the drug/metabolite transporter (DMT) superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.420 |
HEAR0276 | dxs | HEAR0276 | HEAR0279 | Hypothetical protein; No homology to any previously reported sequences. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.460 |
HEAR0276 | ispA | HEAR0276 | HEAR0278 | Hypothetical protein; No homology to any previously reported sequences. | Geranyltranstransferase (Farnesyl-diphosphate synthase) (FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.539 |
HEAR0276 | xseB | HEAR0276 | HEAR0277 | Hypothetical protein; No homology to any previously reported sequences. | Exodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) (XseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.539 |
HEAR1696 | xseB | HEAR1696 | HEAR0277 | Conserved hypothetical protein, induce by arsenic; Homologs of previously reported genes of unknown function. | Exodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) (XseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.922 |
dxs | HEAR0276 | HEAR0279 | HEAR0276 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Hypothetical protein; No homology to any previously reported sequences. | 0.460 |
dxs | folE2 | HEAR0279 | HEAR0280 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.612 |
dxs | ispA | HEAR0279 | HEAR0278 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Geranyltranstransferase (Farnesyl-diphosphate synthase) (FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.863 |
dxs | xseB | HEAR0279 | HEAR0277 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Exodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) (XseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.745 |
fliA | xseB | HEAR1314 | HEAR0277 | RNA polymerase sigma factor for flagellar operon (Sigma-F factor) (Sigma-27) (Sigma-28); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. | Exodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) (XseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.572 |
folE2 | HEAR0274 | HEAR0280 | HEAR0274 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Putative permease of the drug/metabolite transporter (DMT) superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.559 |
folE2 | dxs | HEAR0280 | HEAR0279 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.612 |
folE2 | ispA | HEAR0280 | HEAR0278 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Geranyltranstransferase (Farnesyl-diphosphate synthase) (FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.542 |
folE2 | xseB | HEAR0280 | HEAR0277 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Exodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) (XseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.542 |
hemC | ispA | HEAR1007 | HEAR0278 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Geranyltranstransferase (Farnesyl-diphosphate synthase) (FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.464 |
hemC | ispB | HEAR1007 | HEAR2788 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.510 |