node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
accC | aceB | HEAR2763 | HEAR1688 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | 0.903 |
accC | acsA | HEAR2763 | HEAR0921 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.924 |
accC | gltA | HEAR2763 | HEAR1773 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. | 0.833 |
accC | leuA1 | HEAR2763 | HEAR1035 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.903 |
accC | leuA2 | HEAR2763 | HEAR1242 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.903 |
accC | mmsA | HEAR2763 | HEAR3421 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.916 |
accC | phbA | HEAR2763 | HEAR0577 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.912 |
aceB | accC | HEAR1688 | HEAR2763 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.903 |
aceB | ackA | HEAR1688 | HEAR1515 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.792 |
aceB | acsA | HEAR1688 | HEAR0921 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.957 |
aceB | gltA | HEAR1688 | HEAR1773 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. | 0.954 |
aceB | leuA1 | HEAR1688 | HEAR1035 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.907 |
aceB | leuA2 | HEAR1688 | HEAR1242 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.907 |
aceB | mmsA | HEAR1688 | HEAR3421 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.836 |
aceB | phbA | HEAR1688 | HEAR0577 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.931 |
aceB | prpC | HEAR1688 | HEAR3267 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | 2-methylcitrate synthase (Methylcitrate synthase) (Citrate synthase 2); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. | 0.564 |
aceB | prpE | HEAR1688 | HEAR3269 | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.588 |
ackA | aceB | HEAR1515 | HEAR1688 | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Malate synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the malate synthase family. | 0.792 |
ackA | acsA | HEAR1515 | HEAR0921 | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.930 |
ackA | gltA | HEAR1515 | HEAR1773 | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. | 0.402 |