STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEAR3105Putative 3-Deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P phosphatase) kdsC-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (179 aa)    
Predicted Functional Partners:
kdsD
Arabinose 5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SIS family. GutQ/KpsF subfamily.
  
 0.995
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase (KDO synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family.
  
 0.989
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.983
HEAR3106
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.918
HEAR1126
N-acylneuraminate-9-phosphate synthase; Function of strongly homologous gene; enzyme.
    
 0.885
HEAR3108
Putative ABC-type transport system, ATPase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
  
 0.836
lpxA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.746
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.740
lpxK
Tetraacyldisaccharide 4' kinase (lipid A 4'kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.734
lptA
Conserved hypothetical protein, putative organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
  
  
 0.719
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
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