STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANY25681.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.922
ANY24093.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.754
ANY22554.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.729
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.722
ANY22547.1
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.659
ANY23270.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.622
ANY23352.1
dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.619
ANY24258.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.615
ANY21436.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.
 
     0.608
ANY23766.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.589
Your Current Organism:
Gordonia terrae
NCBI taxonomy Id: 2055
Other names: ATCC 25594, CCUG 34959, CIP 104295, DSM 43249, G. terrae, Gordona terrae, Gordonia sp. IIPN1, Gordonia terrae K, JCM 3206, JCM 3229, LMG 5369, LMG:5369, Methylobacteriaceae bacterium GB31, Methylobacteriaceae bacterium GX1, Methylobacteriaceae bacterium ST1, NBRC 100016, NCTC 10669, NRRL B-16283, Rhodococcus terrae, Rothia sp. K, strain 3612
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