STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANY21614.1Regulator of ribonuclease activity; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (163 aa)    
Predicted Functional Partners:
ANY21615.1
Succinic semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
     
 0.793
ANY21613.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.739
ANY22044.1
Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.584
ANY25717.1
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.569
ANY25718.1
lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.569
ANY21612.1
RNA polymerase subunit sigma; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.510
ANY25628.1
Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.510
ANY21616.1
Glucose dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.463
mscL
Mechanosensitive ion channel protein MscL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
  
  
 0.443
ANY21618.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.411
Your Current Organism:
Gordonia terrae
NCBI taxonomy Id: 2055
Other names: ATCC 25594, CCUG 34959, CIP 104295, DSM 43249, G. terrae, Gordona terrae, Gordonia sp. IIPN1, Gordonia terrae K, JCM 3206, JCM 3229, LMG 5369, LMG:5369, Methylobacteriaceae bacterium GB31, Methylobacteriaceae bacterium GX1, Methylobacteriaceae bacterium ST1, NBRC 100016, NCTC 10669, NRRL B-16283, Rhodococcus terrae, Rothia sp. K, strain 3612
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