STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (267 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.995
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.984
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.949
coaA
Type I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.940
coaBC
Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
 
 0.935
ANY24888.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.935
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
 0.619
lysS
lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.583
ANY24876.1
Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.574
ANY22138.1
Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.569
Your Current Organism:
Gordonia terrae
NCBI taxonomy Id: 2055
Other names: ATCC 25594, CCUG 34959, CIP 104295, DSM 43249, G. terrae, Gordona terrae, Gordonia sp. IIPN1, Gordonia terrae K, JCM 3206, JCM 3229, LMG 5369, LMG:5369, Methylobacteriaceae bacterium GB31, Methylobacteriaceae bacterium GX1, Methylobacteriaceae bacterium ST1, NBRC 100016, NCTC 10669, NRRL B-16283, Rhodococcus terrae, Rothia sp. K, strain 3612
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