STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVG20_g10368SH3 domain-containing protein. (298 aa)    
Predicted Functional Partners:
EVG20_g3221
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.748
EVG20_g3514
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.573
EVG20_g4043
Uncharacterized protein.
   
 
 0.568
EVG20_g214
Uncharacterized protein.
    
 
 0.539
EVG20_g5415
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.538
EVG20_g5970
MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 0.533
EVG20_g11070
Protein kinase domain-containing protein.
    
 
 0.504
EVG20_g9958
Uncharacterized protein.
    
 
 0.504
EVG20_g2529
Uncharacterized protein; Belongs to the actin family.
   
 
 0.470
EVG20_g9421
BAR domain-containing protein.
    
 
 0.456
Your Current Organism:
Dentipellis fragilis
NCBI taxonomy Id: 205917
Other names: D. fragilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.