STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVG20_g10057NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (310 aa)    
Predicted Functional Partners:
EVG20_g3189
Deacetylase sirtuin-type domain-containing protein.
  
 
 0.858
EVG20_g1446
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
    
 0.827
EVG20_g2876
CN hydrolase domain-containing protein.
    
 0.816
EVG20_g11469
Uncharacterized protein.
   
 
 0.790
EVG20_g1372
Nudix hydrolase domain-containing protein.
    
 0.784
EVG20_g3092
Uncharacterized protein.
    
 0.778
EVG20_g5645
Uncharacterized protein.
    
  0.771
EVG20_g8802
Uncharacterized protein.
    
 0.770
EVG20_g1663
IU_nuc_hydro domain-containing protein.
   
 
 0.767
EVG20_g2094
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.729
Your Current Organism:
Dentipellis fragilis
NCBI taxonomy Id: 205917
Other names: D. fragilis
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