EVG20_g7595 protein (Dentipellis fragilis) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

EVG20_g7595

Uncharacterized protein. (262 aa)

Predicted Functional Partners:

EVG20_g9677

0.764

EVG20_g8045

0.596

EVG20_g5421

0.596

EVG20_g1362

0.596

EVG20_g1391

0.570

EVG20_g1998

0.570

BNA5

0.527

EVG20_g7412

0.505

EVG20_g95

0.505

COQ5

0.496

Your Current Organism:

Dentipellis fragilis

NCBI taxonomy Id: 205917
Other names: D. fragilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA5	EVG20_g7595	A0A4Y9Z980	A0A4Y9YBS3	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein.	0.527
BNA5	EVG20_g9677	A0A4Y9Z980	A0A4Y9XWL0	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein.	0.793
COQ5	EVG20_g1362	A0A4Y9Z1V8	A0A4Y9ZAS9	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Uncharacterized protein.	0.666
COQ5	EVG20_g5421	A0A4Y9Z1V8	A0A4Y9YSY8	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Uncharacterized protein.	0.757
COQ5	EVG20_g7595	A0A4Y9Z1V8	A0A4Y9YBS3	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Uncharacterized protein.	0.496
COQ5	EVG20_g8045	A0A4Y9Z1V8	A0A4Y9YAG6	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Uncharacterized protein.	0.709
EVG20_g1362	COQ5	A0A4Y9ZAS9	A0A4Y9Z1V8	Uncharacterized protein.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.666
EVG20_g1362	EVG20_g7595	A0A4Y9ZAS9	A0A4Y9YBS3	Uncharacterized protein.	Uncharacterized protein.	0.596
EVG20_g1391	EVG20_g1998	A0A4Y9ZAP3	A0A4Y9ZC88	Uncharacterized protein.	Uncharacterized protein.	0.884
EVG20_g1391	EVG20_g7595	A0A4Y9ZAP3	A0A4Y9YBS3	Uncharacterized protein.	Uncharacterized protein.	0.570
EVG20_g1391	EVG20_g9677	A0A4Y9ZAP3	A0A4Y9XWL0	Uncharacterized protein.	Uncharacterized protein.	0.882
EVG20_g1998	EVG20_g1391	A0A4Y9ZC88	A0A4Y9ZAP3	Uncharacterized protein.	Uncharacterized protein.	0.884
EVG20_g1998	EVG20_g7595	A0A4Y9ZC88	A0A4Y9YBS3	Uncharacterized protein.	Uncharacterized protein.	0.570
EVG20_g1998	EVG20_g9677	A0A4Y9ZC88	A0A4Y9XWL0	Uncharacterized protein.	Uncharacterized protein.	0.882
EVG20_g5421	COQ5	A0A4Y9YSY8	A0A4Y9Z1V8	Uncharacterized protein.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.757
EVG20_g5421	EVG20_g7595	A0A4Y9YSY8	A0A4Y9YBS3	Uncharacterized protein.	Uncharacterized protein.	0.596
EVG20_g7412	EVG20_g7595	A0A4Y9YE17	A0A4Y9YBS3	F-box domain-containing protein.	Uncharacterized protein.	0.505
EVG20_g7595	BNA5	A0A4Y9YBS3	A0A4Y9Z980	Uncharacterized protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.527
EVG20_g7595	COQ5	A0A4Y9YBS3	A0A4Y9Z1V8	Uncharacterized protein.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.496
EVG20_g7595	EVG20_g1362	A0A4Y9YBS3	A0A4Y9ZAS9	Uncharacterized protein.	Uncharacterized protein.	0.596

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.845

expected number of edges:

17

PPI enrichment p-value:

7.6e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006096

Glycolytic process

8 of 10

2.52

7.2

1.70e-15

GO:0006091

Generation of precursor metabolites and energy

10 of 117

1.55

3.29

1.41e-13

GO:0006006

Glucose metabolic process

4 of 12

2.14

2.92

1.07e-06

GO:0019637

Organophosphate metabolic process

9 of 180

1.32

2.1

6.90e-10

GO:1901135

Carbohydrate derivative metabolic process

9 of 220

1.23

1.8

3.39e-09

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1199

0.54

0.43

0.0016

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1317

Glycolytic process

9 of 10

2.58

8.76

6.56e-19

CL:1315

Glycolytic process, and Schiff base

10 of 16

2.42

8.67

4.93e-20

CL:1243

Carbon metabolism

11 of 58

1.9

5.76

9.23e-19

CL:1319

Glycolysis

5 of 5

2.62

4.76

7.41e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00010

Glycolysis / Gluconeogenesis

10 of 41

2.01

6.1

1.45e-17

map01200

Carbon metabolism

11 of 101

1.66

4.17

6.52e-17

map01230

Biosynthesis of amino acids

9 of 132

1.45

2.66

2.91e-11

map00680

Methane metabolism

4 of 26

1.81

2.23

9.50e-06

map00030

Pentose phosphate pathway

4 of 39

1.63

1.85

3.61e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

9 of 923

0.61

0.44

0.0061

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0324

Glycolysis

8 of 8

2.62

7.96

8.79e-17

KW-0312

Gluconeogenesis

2 of 4

2.32

1.22

0.0054

KW-0963

Cytoplasm

6 of 216

1.06

0.96

0.00046

KW-0460

Magnesium

3 of 83

1.18

0.57

0.0484

KW-0413

Isomerase

3 of 84

1.17

0.57

0.0484

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