EVG20_g7498 protein (Dentipellis fragilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EVG20_g7498

Uncharacterized protein. (842 aa)

Predicted Functional Partners:

EVG20_g4075

0.961

EVG20_g1992

0.959

EVG20_g10707

0.940

EVG20_g6949

0.940

EVG20_g9404

0.792

EVG20_g9368

0.773

EVG20_g9506

0.773

EVG20_g9692

0.765

EVG20_g8502

0.765

EVG20_g4949

0.758

Your Current Organism:

Dentipellis fragilis

NCBI taxonomy Id: 205917
Other names: D. fragilis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EVG20_g10707	EVG20_g1992	A0A4Y9XQP7	A0A4Y9Z8B8	Uncharacterized protein.	Signal peptidase subunit 3.	0.992
EVG20_g10707	EVG20_g4075	A0A4Y9XQP7	A0A4Y9YZ72	Uncharacterized protein.	Uncharacterized protein.	0.993
EVG20_g10707	EVG20_g7498	A0A4Y9XQP7	A0A4Y9YCF3	Uncharacterized protein.	Uncharacterized protein.	0.940
EVG20_g1992	EVG20_g10707	A0A4Y9Z8B8	A0A4Y9XQP7	Signal peptidase subunit 3.	Uncharacterized protein.	0.992
EVG20_g1992	EVG20_g4075	A0A4Y9Z8B8	A0A4Y9YZ72	Signal peptidase subunit 3.	Uncharacterized protein.	0.991
EVG20_g1992	EVG20_g6949	A0A4Y9Z8B8	A0A4Y9YLA3	Signal peptidase subunit 3.	HTH cro/C1-type domain-containing protein.	0.970
EVG20_g1992	EVG20_g7498	A0A4Y9Z8B8	A0A4Y9YCF3	Signal peptidase subunit 3.	Uncharacterized protein.	0.959
EVG20_g4075	EVG20_g10707	A0A4Y9YZ72	A0A4Y9XQP7	Uncharacterized protein.	Uncharacterized protein.	0.993
EVG20_g4075	EVG20_g1992	A0A4Y9YZ72	A0A4Y9Z8B8	Uncharacterized protein.	Signal peptidase subunit 3.	0.991
EVG20_g4075	EVG20_g6949	A0A4Y9YZ72	A0A4Y9YLA3	Uncharacterized protein.	HTH cro/C1-type domain-containing protein.	0.977
EVG20_g4075	EVG20_g7498	A0A4Y9YZ72	A0A4Y9YCF3	Uncharacterized protein.	Uncharacterized protein.	0.961
EVG20_g4949	EVG20_g7498	A0A4Y9YVA1	A0A4Y9YCF3	Uncharacterized protein.	Uncharacterized protein.	0.758
EVG20_g4949	EVG20_g8502	A0A4Y9YVA1	A0A4Y9Y4Y5	Uncharacterized protein.	Uncharacterized protein.	0.923
EVG20_g4949	EVG20_g9368	A0A4Y9YVA1	A0A4Y9Y0Q0	Uncharacterized protein.	Uncharacterized protein.	0.925
EVG20_g4949	EVG20_g9404	A0A4Y9YVA1	A0A4Y9XYL9	Uncharacterized protein.	Uncharacterized protein.	0.970
EVG20_g4949	EVG20_g9506	A0A4Y9YVA1	A0A4Y9Y216	Uncharacterized protein.	DEP domain-containing protein.	0.925
EVG20_g4949	EVG20_g9692	A0A4Y9YVA1	A0A4Y9XWF5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.970
EVG20_g6949	EVG20_g1992	A0A4Y9YLA3	A0A4Y9Z8B8	HTH cro/C1-type domain-containing protein.	Signal peptidase subunit 3.	0.970
EVG20_g6949	EVG20_g4075	A0A4Y9YLA3	A0A4Y9YZ72	HTH cro/C1-type domain-containing protein.	Uncharacterized protein.	0.977
EVG20_g6949	EVG20_g7498	A0A4Y9YLA3	A0A4Y9YCF3	HTH cro/C1-type domain-containing protein.	Uncharacterized protein.	0.940

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.88

expected number of edges:

12

PPI enrichment p-value:

7.14e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006099

Tricarboxylic acid cycle

4 of 30

2.15

2.12

6.84e-05

GO:0006097

Glyoxylate cycle

2 of 2

3.03

1.41

0.0029

GO:0005975

Carbohydrate metabolic process

6 of 447

1.16

0.96

0.0014

GO:0006094

Gluconeogenesis

2 of 12

2.25

0.84

0.0289

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046912

Acyltransferase activity, acyl groups converted into alkyl on transfer

3 of 13

2.39

1.75

0.00054

GO:0042132

Fructose 1,6-bisphosphate 1-phosphatase activity

2 of 2

3.03

1.34

0.0038

GO:0004108

Citrate (Si)-synthase activity

2 of 2

3.03

1.34

0.0038

GO:0016746

Acyltransferase activity

4 of 188

1.36

0.95

0.0055

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009514

Glyoxysome

2 of 2

3.03

1.33

0.0039

GO:0042597

Periplasmic space

2 of 4

2.73

1.27

0.0049

GO:0005777

Peroxisome

3 of 82

1.59

0.93

0.0118

GO:0005737

Cytoplasm

11 of 4517

0.42

0.32

0.0074

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9454

Citrate synthase, and Citrate metabolic process

2 of 5

2.63

0.82

0.0323

CL:17099

Mixed, incl. Sequestering of actin monomers, and C4-dicarboxylate transmembrane transporter activity

2 of 5

2.63

0.82

0.0323

CL:11084

Glyoxysome, and Isocitrate lyase

2 of 5

2.63

0.82

0.0323

CL:10111

Glycolytic process, and Insulin effects increased synthesis of Xylulose-5-Phosphate

2 of 18

2.07

0.74

0.0415

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

plj01200

Carbon metabolism

6 of 113

1.75

2.86

5.15e-08

plj00630

Glyoxylate and dicarboxylate metabolism

4 of 36

2.07

2.72

2.29e-06

plj00020

Citrate cycle (TCA cycle)

2 of 28

1.88

1.06

0.0084

plj01210

2-Oxocarboxylic acid metabolism

2 of 32

1.82

1.04

0.0090

plj01110

Biosynthesis of secondary metabolites

5 of 415

1.11

0.96

0.00090

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009514

Glyoxysome

2 of 3

2.85

1.17

0.0078

GOCC:0042597

Periplasmic space

2 of 13

2.22

0.76

0.0406

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00316

Fructose-1-6-bisphosphatase, N-terminal domain

2 of 2

3.03

1.28

0.0050

PF00285

Citrate synthase, C-terminal domain

2 of 3

2.85

1.27

0.0050

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR044015

Fructose-1-6-bisphosphatase class 1, C-terminal

2 of 2

3.03

1.03

0.0141

IPR033391

Fructose-1-6-bisphosphatase class I, N-terminal

2 of 2

3.03

1.03

0.0141

IPR020548

Fructose-1,6-bisphosphatase, active site

2 of 2

3.03

1.03

0.0141

IPR019810

Citrate synthase active site

2 of 2

3.03

1.03

0.0141

IPR000146

Fructose-1,6-bisphosphatase class 1

2 of 2

3.03

1.03

0.0141

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (10%) [HD]

Permalink

Network

Fusion

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Neighborhood

© STRING Consortium 2024

Credits

Access

Info

About