STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVG20_g3567Uncharacterized protein. (1038 aa)    
Predicted Functional Partners:
EVG20_g2859
DNA_MISMATCH_REPAIR_2 domain-containing protein.
  
0.996
EVG20_g11272
DNA_mis_repair domain-containing protein.
 
 0.931
EVG20_g3609
DNA_mis_repair domain-containing protein.
 
 0.930
EVG20_g9258
Uncharacterized protein.
 
 0.928
EVG20_g1664
MutL_C domain-containing protein.
  
 0.899
EVG20_g6861
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.895
EVG20_g4701
Uncharacterized protein.
  
 0.895
EVG20_g5332
Uncharacterized protein.
   
 0.842
EVG20_g4408
Uncharacterized protein.
    
 0.777
EVG20_g3279
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.777
Your Current Organism:
Dentipellis fragilis
NCBI taxonomy Id: 205917
Other names: D. fragilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.