STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVG20_g3751Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1047 aa)    
Predicted Functional Partners:
EVG20_g3609
DNA_mis_repair domain-containing protein.
    
 0.957
EVG20_g9258
Uncharacterized protein.
    
 0.922
EVG20_g4701
Uncharacterized protein.
    
 0.814
EVG20_g4749
ERCC4 domain-containing protein.
    
 0.807
SLX1
Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
   
 
 0.789
EVG20_g712
DRMBL domain-containing protein.
    
 0.789
EVG20_g8642
Uncharacterized protein.
     
 0.777
EVG20_g7311
AA_TRNA_LIGASE_II domain-containing protein.
   
 
 0.763
EVG20_g5266
POLAc domain-containing protein.
   
 
 0.756
EVG20_g381
Uncharacterized protein.
     
 0.749
Your Current Organism:
Dentipellis fragilis
NCBI taxonomy Id: 205917
Other names: D. fragilis
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