STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVG20_g3223B30.2/SPRY domain-containing protein. (661 aa)    
Predicted Functional Partners:
EVG20_g6185
Uncharacterized protein.
    
 0.995
EVG20_g7575
WD_REPEATS_REGION domain-containing protein.
   
 0.963
EVG20_g5937
Histone domain-containing protein.
    
 0.939
EVG20_g2951
Histone H3; Belongs to the histone H3 family.
    
 0.939
EVG20_g2094
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.936
EVG20_g2950
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.933
EVG20_g1070
PHD-type domain-containing protein.
   
 0.912
EVG20_g6375
Uncharacterized protein.
    
 0.903
EVG20_g4350
Ubiquitin-like domain-containing protein.
    
   0.903
EVG20_g3488
Zn(2)-C6 fungal-type domain-containing protein.
    
 0.903
Your Current Organism:
Dentipellis fragilis
NCBI taxonomy Id: 205917
Other names: D. fragilis
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.