STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (303 aa)    
Predicted Functional Partners:
EVG20_g941
Uncharacterized protein.
 
      0.857
EVG20_g6002
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.833
EVG20_g7834
Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family.
   
 0.769
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
   
 0.764
EVG20_g6282
Uncharacterized protein.
    
 0.749
EVG20_g1029
Uncharacterized protein.
  
 
 0.746
EVG20_g5290
Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family.
     
 0.716
EVG20_g1200
Uncharacterized protein; Belongs to the complex I 49 kDa subunit family.
     
 0.716
EVG20_g1627
Uncharacterized protein; Belongs to the complex I 75 kDa subunit family.
    
 0.715
EVG20_g11450
ABC transmembrane type-1 domain-containing protein.
    
 0.714
Your Current Organism:
Dentipellis fragilis
NCBI taxonomy Id: 205917
Other names: D. fragilis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.