STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECH_0199Conserved hypothetical protein; Identified by similarity to PIR:G97712; match to protein family HMM PF06242. (213 aa)    
Predicted Functional Partners:
ECH_0744
Conserved hypothetical protein; Identified by similarity to PIR:F71632; match to protein family HMM PF07031.
  
   
 0.759
ECH_0232
Tim44-like domain protein; Identified by similarity to GB:AAS13862.1; match to protein family HMM PF04280.
  
     0.745
recO
Putative DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.727
ECH_1118
Putative transcriptional regulator; Identified by similarity to GB:AAC02808.2; match to protein family HMM PF01381.
  
     0.723
ECH_0126
Conserved hypothetical protein; Identified by similarity to GB:AAS14093.1; match to protein family HMM PF06144; match to protein family HMM TIGR01128.
  
     0.711
lysS
lysyl-tRNA synthetase; Identified by similarity to SP:O29052; match to protein family HMM PF01921; match to protein family HMM TIGR00467; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.711
ECH_0576
Conserved hypothetical protein; Identified by similarity to SP:O05113.
  
   
 0.670
yidC
Inner-membrane protein, 60 kDa; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
     0.630
ECH_0874
Disulfide bond formation family protein; Identified by match to protein family HMM PF02600.
  
     0.580
nadK
Putative ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
     0.557
Your Current Organism:
Ehrlichia chaffeensis
NCBI taxonomy Id: 205920
Other names: E. chaffeensis str. Arkansas, Ehrlichia chaffeensis Arkansas, Ehrlichia chaffeensis str. Arkansas
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.