STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECH_0307Identified by match to protein family HMM PF02674. (206 aa)    
Predicted Functional Partners:
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
 0.877
ECH_0306
TRAP transporter, 4TM/12TM fusion protein; Identified by match to protein family HMM PF06808; match to protein family HMM TIGR02123.
       0.832
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by similarity to SP:P12046; match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family.
  
    0.817
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Identified by similarity to SP:P08178; match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878.
   
    0.794
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
   
    0.740
ECH_0482
Putative lipoprotein.
  
     0.719
ECH_0499
Type IV secretion system protein,VirB6 family; Identified by match to protein family HMM PF04610.
 
     0.719
virB6
Type IV secretion system protein VirB6; Identified by similarity to GB:AAM00403.1; match to protein family HMM PF04610.
  
     0.709
ECH_0176
Conserved hypothetical protein; Identified by similarity to GB:AAS14671.1.
  
     0.701
ECH_0362
Putative phosphoribosylformylglycinamidine synthase I; Identified by similarity to SP:P15254.
   
    0.692
Your Current Organism:
Ehrlichia chaffeensis
NCBI taxonomy Id: 205920
Other names: E. chaffeensis str. Arkansas, Ehrlichia chaffeensis Arkansas, Ehrlichia chaffeensis str. Arkansas
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