ECH_0331 protein (Ehrlichia chaffeensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ECH_0331

RDD family protein; Identified by match to protein family HMM PF06271. (163 aa)

Predicted Functional Partners:

ECH_0332

0.841

ispB

0.563

ECH_0438

0.559

ECH_0781

0.559

ECH_0333

0.515

aspS

0.459

mutL

0.445

Your Current Organism:

Ehrlichia chaffeensis

NCBI taxonomy Id: 205920
Other names: E. chaffeensis str. Arkansas, Ehrlichia chaffeensis Arkansas, Ehrlichia chaffeensis str. Arkansas

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ECH_0331	ECH_0332	ECH_0331	ECH_0332	RDD family protein; Identified by match to protein family HMM PF06271.	HAD-superfamily hydrolase, subfamily IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	0.841
ECH_0331	ECH_0333	ECH_0331	ECH_0333	RDD family protein; Identified by match to protein family HMM PF06271.	Serine hydroxymethyltransferase domain protein; Identified by similarity to SP:P00477.	0.515
ECH_0331	ECH_0438	ECH_0331	ECH_0438	RDD family protein; Identified by match to protein family HMM PF06271.	Identified by match to protein family HMM PF01235.	0.559
ECH_0331	ECH_0781	ECH_0331	ECH_0781	RDD family protein; Identified by match to protein family HMM PF06271.	Identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835.	0.559
ECH_0331	aspS	ECH_0331	ECH_0334	RDD family protein; Identified by match to protein family HMM PF06271.	aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	0.459
ECH_0331	ispB	ECH_0331	ECH_0088	RDD family protein; Identified by match to protein family HMM PF06271.	Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	0.563
ECH_0331	mutL	ECH_0331	ECH_0884	RDD family protein; Identified by match to protein family HMM PF06271.	DNA mismatch repair protein, MutL/HexB family; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.445
ECH_0332	ECH_0331	ECH_0332	ECH_0331	HAD-superfamily hydrolase, subfamily IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	RDD family protein; Identified by match to protein family HMM PF06271.	0.841
ECH_0332	ECH_0333	ECH_0332	ECH_0333	HAD-superfamily hydrolase, subfamily IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	Serine hydroxymethyltransferase domain protein; Identified by similarity to SP:P00477.	0.561
ECH_0332	aspS	ECH_0332	ECH_0334	HAD-superfamily hydrolase, subfamily IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	0.515
ECH_0333	ECH_0331	ECH_0333	ECH_0331	Serine hydroxymethyltransferase domain protein; Identified by similarity to SP:P00477.	RDD family protein; Identified by match to protein family HMM PF06271.	0.515
ECH_0333	ECH_0332	ECH_0333	ECH_0332	Serine hydroxymethyltransferase domain protein; Identified by similarity to SP:P00477.	HAD-superfamily hydrolase, subfamily IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	0.561
ECH_0333	aspS	ECH_0333	ECH_0334	Serine hydroxymethyltransferase domain protein; Identified by similarity to SP:P00477.	aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	0.640
ECH_0438	ECH_0331	ECH_0438	ECH_0331	Identified by match to protein family HMM PF01235.	RDD family protein; Identified by match to protein family HMM PF06271.	0.559
ECH_0438	ispB	ECH_0438	ECH_0088	Identified by match to protein family HMM PF01235.	Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	0.563
ECH_0438	mutL	ECH_0438	ECH_0884	Identified by match to protein family HMM PF01235.	DNA mismatch repair protein, MutL/HexB family; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.425
ECH_0781	ECH_0331	ECH_0781	ECH_0331	Identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835.	RDD family protein; Identified by match to protein family HMM PF06271.	0.559
ECH_0781	ispB	ECH_0781	ECH_0088	Identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835.	Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	0.563
ECH_0781	mutL	ECH_0781	ECH_0884	Identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835.	DNA mismatch repair protein, MutL/HexB family; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.425
aspS	ECH_0331	ECH_0334	ECH_0331	aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	RDD family protein; Identified by match to protein family HMM PF06271.	0.459