STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECH_0331RDD family protein; Identified by match to protein family HMM PF06271. (163 aa)    
Predicted Functional Partners:
ECH_0332
HAD-superfamily hydrolase, subfamily IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.
       0.832
mutL
DNA mismatch repair protein, MutL/HexB family; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
     
 0.587
ispB
Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
      
 0.584
thiC
Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
     
 0.577
ECH_0277
DNA-3-methyladenine glycosylase; Identified by similarity to PIR:S12059; match to protein family HMM PF02245; match to protein family HMM TIGR00567; Belongs to the DNA glycosylase MPG family.
      
 0.572
ECH_0438
Identified by match to protein family HMM PF01235.
      
 0.570
ECH_0781
Identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835.
      
 0.570
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
      
 0.569
ECH_1001
Aspartate kinase; Identified by similarity to SP:P08495; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
      
 0.569
ECH_0333
Serine hydroxymethyltransferase domain protein; Identified by similarity to SP:P00477.
       0.515
Your Current Organism:
Ehrlichia chaffeensis
NCBI taxonomy Id: 205920
Other names: E. chaffeensis str. Arkansas, Ehrlichia chaffeensis Arkansas, Ehrlichia chaffeensis str. Arkansas
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