STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECH_0636Cytochrome c biogenesis family protein; Possible subunit of a heme lyase. (134 aa)    
Predicted Functional Partners:
ccmF
Cytochrome c-type biogenesis protein CcmF; Identified by match to protein family HMM PF01578.
 
  
 0.934
ECH_0304
Putative thiol:disulfide oxidoreductase; Identified by similarity to SP:P33926.
 
  
 0.898
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.886
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
   
 0.867
ECH_0635
Hypothetical protein; Identified by Glimmer2; putative.
       0.832
ECH_0065
Putative heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
   
 0.814
ECH_0634
Iron-sulfur cluster binding protein; Identified by match to protein family HMM PF00111.
       0.749
ECH_0295
Putative heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.732
ECH_0631
Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.
       0.693
hscB
Co-chaperone Hsc20; Identified by similarity to SP:P36540; match to protein family HMM PF00226; match to protein family HMM PF07743; Belongs to the HscB family.
       0.693
Your Current Organism:
Ehrlichia chaffeensis
NCBI taxonomy Id: 205920
Other names: E. chaffeensis str. Arkansas, Ehrlichia chaffeensis Arkansas, Ehrlichia chaffeensis str. Arkansas
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