STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECH_0664Hypothetical protein; Identified by Glimmer2; putative. (198 aa)    
Predicted Functional Partners:
ECH_0665
Phage uncharacterized protein; Identified by match to protein family HMM TIGR01630.
     
 0.851
ECH_0662
Conserved hypothetical protein; Identified by similarity to GB:AAS13839.1.
     
 0.774
ECH_0661
Conserved hypothetical protein; Identified by similarity to GB:AAS13838.1.
     
 0.729
ECH_0660
Conserved hypothetical protein; Identified by similarity to GB:AAS13837.1; match to protein family HMM TIGR02215.
     
 0.725
ECH_0659
Conserved hypothetical protein; Identified by similarity to GB:AAS13835.1.
     
 0.698
ECH_0663
Conserved hypothetical protein; Identified by similarity to GB:AAS13840.1.
     
0.601
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.567
ECH_0067
Cation diffusion facilitator transporter family protein; Identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297.
      
 0.561
ECH_0189
Putative iron-binding protein; Identified by similarity to GB:AAD03802.1; match to protein family HMM PF01547.
      
 0.561
Your Current Organism:
Ehrlichia chaffeensis
NCBI taxonomy Id: 205920
Other names: E. chaffeensis str. Arkansas, Ehrlichia chaffeensis Arkansas, Ehrlichia chaffeensis str. Arkansas
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.