Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECH_0848biotin--acetyl-CoA-carboxylase ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. (251 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.949
pccA
propionyl-CoA carboxylase, alpha subunit; Identified by similarity to GB:AAL66189.1; match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786.
 
  
 0.930
pccB
propionyl-CoA carboxylase, beta subunit; Identified by similarity to GB:AAB28900.1; match to protein family HMM PF01039.
  
 
 0.841
ECH_0966
Metallo-beta-lactamase family, beta-CASP subfamily; Identified by match to protein family HMM PF00753; match to protein family HMM PF07521.
      0.705
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by similarity to SP:P71019; match to protein family HMM PF00698; match to protein family HMM TIGR00128.
 
   
 0.656
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.647
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.591
nuoM
NADH dehydrogenase I, M subunit; Identified by similarity to SP:P29925; match to protein family HMM PF00361; match to protein family HMM TIGR01972.
  
  
 0.557
tadA
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.551
ECH_0847
Identified by match to protein family HMM PF02798.
     
 0.531
Your Current Organism:
Ehrlichia chaffeensis
NCBI taxonomy Id: 205920
Other names: E. chaffeensis str. Arkansas, Ehrlichia chaffeensis Arkansas, Ehrlichia chaffeensis str. Arkansas
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