Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECH_0966Metallo-beta-lactamase family, beta-CASP subfamily; Identified by match to protein family HMM PF00753; match to protein family HMM PF07521. (540 aa)    
Predicted Functional Partners:
ECH_0848
biotin--acetyl-CoA-carboxylase ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121.
      0.705
ispB
Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
  
    0.616
ECH_0455
Putative geranyltranstransferase; Identified by similarity to SP:Q08291; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
  
    0.616
ECH_0964
Serine/threonine phosphoprotein phosphatase; Identified by match to protein family HMM PF00149.
       0.470
ECH_0965
Hypothetical protein; Identified by Glimmer2; putative.
       0.470
rpsO
Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
  
 0.420
ybeY
Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 
  
 0.416
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
 
   
 0.414
rsfS
Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.409
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.406
Your Current Organism:
Ehrlichia chaffeensis
NCBI taxonomy Id: 205920
Other names: E. chaffeensis str. Arkansas, Ehrlichia chaffeensis Arkansas, Ehrlichia chaffeensis str. Arkansas
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