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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ66326.1Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (286 aa)    
Predicted Functional Partners:
KIQ63231.1
Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.847
add
Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
  
 
 0.841
KIQ62361.1
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
  
0.829
KIQ63825.1
Spermidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.804
KIQ62220.1
Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.802
KIQ63640.1
Metalloenzyme domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.802
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 
 0.800
apt-2
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 
 0.795
KIQ65121.1
Hydroxydechloroatrazine ethylaminohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.790
KIQ64411.1
Nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.781
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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