STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ66430.1Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)    
Predicted Functional Partners:
KIQ66428.1
Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.965
KIQ64710.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.958
KIQ66884.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.951
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.948
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
 
 
 0.944
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
 
 
 0.933
KIQ67246.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.927
KIQ66429.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.925
KIQ66427.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.908
KIQ66426.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.882
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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