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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ64271.1IMPACT family member yvyE; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)    
Predicted Functional Partners:
KIQ66601.1
2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.682
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
  0.659
KIQ64378.1
Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.656
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
    
  0.651
KIQ64956.1
tRNA synthetase RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.647
KIQ66231.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.613
KIQ62856.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.613
KIQ64717.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.589
KIQ65082.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.588
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
     0.582
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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