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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ65833.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)    
Predicted Functional Partners:
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.759
KIQ62015.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.748
KIQ64234.1
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.715
KIQ63593.1
Anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.710
arc
ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
    0.701
KIQ64376.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.678
KIQ64284.1
Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.667
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
       0.648
KIQ64286.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.580
KIQ65880.1
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.569
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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