STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ65852.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)    
Predicted Functional Partners:
KIQ64359.1
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.695
KIQ64366.1
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.612
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.612
KIQ63628.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.460
KIQ62049.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.416
KIQ62544.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.416
KIQ62881.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.416
KIQ63623.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.416
KIQ67299.1
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.414
KIQ65910.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.414
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.