STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (316 aa)    
Predicted Functional Partners:
cobQ
Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.997
KIQ64519.1
Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.989
cobH
Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.968
KIQ65215.1
precorrin-3B C17-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.963
KIQ61850.1
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.963
KIQ65213.1
Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.953
KIQ65220.1
Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
  
 0.953
cobB
Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 0.952
KIQ64510.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.943
KIQ66976.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.936
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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