STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ64649.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.996
KIQ63406.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.979
grpE
GrpE protein HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...]
 
 
 0.969
KIQ64919.1
Heat shock protein 90; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.948
KIQ64412.1
Regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.930
KIQ64710.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.928
KIQ64029.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.928
KIQ64708.1
Tyrocidine synthase 3; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.919
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.901
rplQ
50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.892
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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