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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ65035.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)    
Predicted Functional Partners:
KIQ67051.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.680
KIQ63786.1
Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.645
KIQ62538.1
Crystallin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.566
KIQ67006.1
Ribosylglycohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.531
KIQ63139.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.508
KIQ65614.1
Appr-1-p processing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.493
KIQ61507.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.451
KIQ66167.1
2'-5' RNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.450
KIQ62536.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.430
KIQ65018.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.412
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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