Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KIQ65290.1Peptidyl-prolyl cis-trans isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)    
Predicted Functional Partners:
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
    0.827
infA-2
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
    0.827
KIQ64919.1
Heat shock protein 90; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.728
KIQ64029.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.728
KIQ65291.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.719
KIQ65292.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.719
KIQ65293.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.719
KIQ62842.1
Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.
    
   0.698
KIQ67103.1
Signal transduction protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.669
KIQ66037.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.665
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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