STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ65433.1Ohr subfamily peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)    
Predicted Functional Partners:
KIQ65432.1
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.963
KIQ64889.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.866
KIQ64803.1
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family.
  
  
 0.638
KIQ62030.1
NADP-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.542
KIQ66536.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0337 (CsbD) family.
   
  
 0.519
KIQ64999.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.511
KIQ66631.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.491
KIQ65839.1
Regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.485
KIQ63250.1
Alpha,alpha-trehalose-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.483
grpE
GrpE protein HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...]
      
 0.480
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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