STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (316 aa)    
Predicted Functional Partners:
KIQ64710.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.984
KIQ65223.1
acetyl-CoA carboxyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.977
accD
acetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 
 0.977
KIQ66428.1
Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.954
KIQ62025.1
ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.950
KIQ63153.1
malonyl-CoA--acyl carrier protein transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.935
KIQ66884.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.934
KIQ66426.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.924
KIQ66427.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.913
KIQ66429.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.913
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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