STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ63829.1Dimethylallyltranstransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (357 aa)    
Predicted Functional Partners:
KIQ61543.1
Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.972
KIQ61541.1
Squalene-hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.968
KIQ63830.1
Squalene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.930
KIQ63368.1
Geosmin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.916
KIQ62059.1
UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.890
KIQ65726.1
Isoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.888
KIQ64190.1
UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.873
KIQ65358.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.841
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.829
cyc1
Hypothetical protein; Involved in the production of the isoprenoid antibiotic terpentecin. Converts geranylgeranyl diphosphate (GGDP) into terpentedienol diphosphate (TDP) by a protonation-initiated cyclisation.
 
 
 0.819
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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