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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ62006.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)    
Predicted Functional Partners:
KIQ62005.1
ATP/GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.994
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.985
KIQ62004.1
HAD superfamily hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    0.958
KIQ62007.1
ATP/GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.901
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.845
KIQ62008.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.844
KIQ65884.1
Stress-induced protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.795
KIQ65876.1
Tellurium resistance protein terZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.794
KIQ66858.1
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.788
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.780
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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