STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ62067.1Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)    
Predicted Functional Partners:
KIQ65200.1
Porin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.576
KIQ62068.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.551
KIQ62069.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.551
KIQ62066.1
Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.529
KIQ66884.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.493
KIQ65707.1
2,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.470
KIQ63827.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.462
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
   0.459
KIQ64710.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.458
KIQ62290.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.449
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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