STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ63948.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)    
Predicted Functional Partners:
KIQ63947.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.849
KIQ62147.1
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.777
KIQ62144.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.735
KIQ64942.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.699
KIQ62146.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.690
KIQ61819.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.629
KIQ62145.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.618
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
  
 0.544
KIQ64359.1
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.540
htpX
Heat shock protein HtpX; Metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family.
   
    0.512
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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