close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ62248.1HIT family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.616
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
  0.579
KIQ63967.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.547
KIQ64511.1
Acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.531
KIQ62262.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.506
KIQ63263.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.506
KIQ66208.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.487
KIQ66074.1
Endoglucanase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.455
KIQ66866.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.447
KIQ64773.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.442
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.