STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ62476.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)    
Predicted Functional Partners:
KIQ65840.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.965
KIQ64571.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.736
KIQ64001.1
RNA polymerase sigma factor SigD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.689
KIQ66641.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.626
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.619
KIQ66480.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.611
KIQ63386.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.602
KIQ67165.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.599
KIQ64896.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.595
KIQ62474.1
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.590
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.