close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ62789.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)    
Predicted Functional Partners:
KIQ62788.1
Pilus assembly protein TadE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.899
KIQ64045.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.892
KIQ62791.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.719
KIQ66016.1
ATP/GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.587
KIQ66957.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.515
KIQ62790.1
Septum formation initiator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.511
KIQ63013.1
PadR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.454
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.453
KIQ62312.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.447
KIQ64286.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.439
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.