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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ62838.1Peptide hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa)    
Predicted Functional Partners:
KIQ63226.1
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.706
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.690
KIQ62837.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.668
KIQ67094.1
PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.619
KIQ66916.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.581
KIQ65898.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.548
KIQ63971.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.520
KIQ65464.1
Methyltransferase type 12; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.511
KIQ62836.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.511
KIQ64286.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.502
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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