STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crgAMembrane protein; Involved in cell division; Belongs to the CrgA family. (84 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.914
ftsQ
Hypothetical protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
 
 
 0.893
KIQ63880.1
Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.823
whiA
Sporulation protein; Involved in cell division and chromosome segregation.
      
 0.815
KIQ61774.1
Cell division protein DivIVA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.779
KIQ64096.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.723
KIQ63033.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.717
KIQ63037.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.659
KIQ64169.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.659
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
      
 0.603
Your Current Organism:
Kitasatospora griseola
NCBI taxonomy Id: 2064
Other names: DSM 43859, IFO 14371, JCM 3339, K. griseola, Kitasatospora sp. OM-5023, NBRC 14371, NRRL B-16229, Streptomyces griseolisporeus, Streptomyces griseolosporeus, VKM Ac-2002, strain AM-9660
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