AKF24206.1 protein (Sulfurovum lithotrophicum)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

AKF24206.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)

Predicted Functional Partners:

AKF24143.1

0.711

AKF24207.1

0.492

AKF24214.1

0.465

AKF25183.1

0.454

Your Current Organism:

Sulfurovum lithotrophicum

NCBI taxonomy Id: 206403
Other names: ATCC BAA-797, JCM 12117, S. lithotrophicum, Sulfurovum lithotrophicum Inagaki et al. 2004, epsilon proteobacterium 42BKT, strain 42BKT

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKF24143.1	AKF24206.1	YH65_01040	YH65_01435	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.711
AKF24143.1	AKF24214.1	YH65_01040	YH65_01480	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.879
AKF24143.1	AKF25183.1	YH65_01040	YH65_07095	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.876
AKF24206.1	AKF24143.1	YH65_01435	YH65_01040	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.711
AKF24206.1	AKF24207.1	YH65_01435	YH65_01440	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.492
AKF24206.1	AKF24214.1	YH65_01435	YH65_01480	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.465
AKF24206.1	AKF25183.1	YH65_01435	YH65_07095	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.454
AKF24207.1	AKF24206.1	YH65_01440	YH65_01435	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.492
AKF24214.1	AKF24143.1	YH65_01480	YH65_01040	dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.879
AKF24214.1	AKF24206.1	YH65_01480	YH65_01435	dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.465
AKF24214.1	AKF25183.1	YH65_01480	YH65_07095	dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.879
AKF25183.1	AKF24143.1	YH65_07095	YH65_01040	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.876
AKF25183.1	AKF24206.1	YH65_07095	YH65_01435	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.454
AKF25183.1	AKF24214.1	YH65_07095	YH65_01480	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.879

Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042843

D-xylose catabolic process

5 of 6

3.02

5.28

1.75e-10

GO:0042559

Pteridine-containing compound biosynthetic process

4 of 13

2.59

3.49

2.53e-07

GO:0006729

Tetrahydrobiopterin biosynthetic process

3 of 5

2.88

2.85

6.01e-06

GO:0044282

Small molecule catabolic process

6 of 215

1.54

2.06

2.33e-06

GO:0019568

Arabinose catabolic process

2 of 2

3.1

1.82

0.00052

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004032

alditol:NADP+ 1-oxidoreductase activity

5 of 7

2.95

5.32

1.35e-10

GO:0016616

Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

6 of 131

1.76

2.74

1.46e-07

GO:0016491

Oxidoreductase activity

9 of 913

1.09

1.33

3.18e-07

GO:0016646

Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor

2 of 13

2.29

1.05

0.0116

GO:0003824

Catalytic activity

11 of 3985

0.54

0.46

0.00026

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:10292

Mixed, incl. Tetrahydrobiopterin metabolic process, and D-xylose catabolic process

7 of 15

2.77

7.39

5.11e-15

CL:10310

Tetrahydrobiopterin metabolic process, and Oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

4 of 6

2.92

4.11

2.63e-08

CL:11394

Pyrimidine deoxyribonucleoside triphosphate metabolic process, and Dihydrofolate metabolic process

2 of 5

2.7

1.26

0.0052

CL:10294

Alditol catabolic process, and D-xylose catabolic process

2 of 5

2.7

1.26

0.0052

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00790

Folate biosynthesis

5 of 50

2.1

3.41

5.51e-08

map00670

One carbon pool by folate

2 of 16

2.2

1.26

0.0043

map00561

Glycerolipid metabolism

2 of 54

1.67

0.76

0.0317

map01100

Metabolic pathways

11 of 2462

0.75

4.36e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-196108

Pregnenolone biosynthesis

5 of 7

2.95

5.43

8.23e-11

MAP-193807

Synthesis of bile acids and bile salts via 27-hydroxycholesterol

5 of 7

2.95

5.43

8.23e-11

MAP-193144

Estrogen biosynthesis

5 of 8

2.89

5.4

8.23e-11

MAP-2162123

Synthesis of Prostaglandins (PG) and Thromboxanes (TX)

5 of 11

2.76

5.25

1.13e-10

MAP-5652227

Fructose biosynthesis

5 of 13

2.68

5.1

1.78e-10

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00248

Aldo/keto reductase family

5 of 38

2.22

3.4

1.16e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR018170

Aldo/keto reductase, conserved site

5 of 8

2.89

5.03

4.34e-10

IPR020471

Aldo-keto reductase

5 of 16

2.59

4.41

3.42e-09

IPR036812

NADP-dependent oxidoreductase domain superfamily

5 of 38

2.22

3.42

1.07e-07

IPR023210

NADP-dependent oxidoreductase domain

5 of 38

2.22

3.42

1.07e-07

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