STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKF24604.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)    
Predicted Functional Partners:
AKF24606.1
Phosphatidylinositol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.955
AKF24605.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.577
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.571
AKF25944.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.492
AKF24603.1
Uroporphyrinogen decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.492
AKF24602.1
Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.489
Your Current Organism:
Sulfurovum lithotrophicum
NCBI taxonomy Id: 206403
Other names: ATCC BAA-797, JCM 12117, S. lithotrophicum, Sulfurovum lithotrophicum Inagaki et al. 2004, epsilon proteobacterium 42BKT, strain 42BKT
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