STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmN50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (357 aa)    
Predicted Functional Partners:
AKF25831.1
Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.813
hisF
Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.800
AKF25484.1
Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.725
AKF24075.1
(dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.721
AKF24080.1
Ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.709
rsmA
16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
     
 0.704
AKF24896.1
Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.642
rnj
Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
     
 0.642
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    0.619
AKF26011.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.596
Your Current Organism:
Sulfurovum lithotrophicum
NCBI taxonomy Id: 206403
Other names: ATCC BAA-797, JCM 12117, S. lithotrophicum, Sulfurovum lithotrophicum Inagaki et al. 2004, epsilon proteobacterium 42BKT, strain 42BKT
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