STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKO71518.1Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (235 aa)    
Predicted Functional Partners:
KKO71670.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.
       0.603
rlmN
50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
     0.562
PgeF
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family.
  
  
 0.557
KKO71669.1
Threonine transporter RhtB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.498
KKO70795.1
23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family.
 
     0.488
murE
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
    0.478
rpmC
50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family.
  
    0.478
KKO71298.1
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
     0.474
KKO71116.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.471
pnp
Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
     0.461
Your Current Organism:
Kerstersia gyiorum
NCBI taxonomy Id: 206506
Other names: Alcaligenes sp. LMG 5906, CCUG 47000, DSM 16618, K. gyiorum, Kerstersia gyiorum Coenye et al. 2003, LMG 5906, LMG:5906, strain API 184-2-84
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